歯周疾患スクリーニングテストに関する研究-唾液中潜血試験紙の有効性について-

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From the view point of health maintenance for adults, it is very important to control periodontal disease. However, scientific, effective and simple screening tests for evaluating periodontal disease are very few, so that many high-risk adults can not be discoverd. For these reasons, I have studied the screening tests of periodontal disease using salivary occult bleeding test strips named "Salivaster-Bld. ®" (S-Bld., Showa yakuhin kako. LTD, ). These test strips were developed by Nakao et al, and I compared these test strips with the urinary occult bleeding test strips named "Hemastix-III®" (H-III, Sankyo CO., LTD.) which had been used for screening tests of periodontal disease for clarifying the differences between both strips. The subjects of this study were 42 adults (Average age: 34.5 years old) and 36 young adults (Average age: 18.9 years old). Two kinds of saliva were used here. One was collected after one minute chewing of sugarless gum (stimulated saliva) and another was collected without chewing (resting saliva). Resting saliva was collected first and stimulated saliva next, and then they were each tested with both strips. Oral examinations were also carried out for taking indices which showed the oral condition. The DMFT index, the OHI, the PMA index, the Russell's PI, the pocket depth, and the gingival crevicular fluid (GCF) measured by Periotron® (Harco electronics LTD.) were used. From the results of S-Bld., the increase of each index value was recognized according to the increase of occult bleeding in stimulated saliva and resting saliva in both adults and young adults. In the index value of the PMA index, the PI, the GCF, and the pocket depth in resting saliva of the adult group, statistical significance was found to be between (-) and (+++). Also, the periodontal disease showed up more clearly in resting saliva rather than in stimulated saliva. On the other hand, stimulated saliva was more suitable in young adults. The reason for this was the difference in the number of missing teeth, which might have an effect on the stimulation from chewing. However, the consistency between each index value and judgement by H-III was not as clear as was expected. Since these test strips were developed for the measurement of occult blood in urine, sensitivity for occult blood was so high that it could detect hemoglobin of 0.015-0.045 mg/dl. This might cause the inconsistency. About 74% of all subjects who were judged negative with S-Bld. were judged positive with H-III. From these results, and from the validity of the screening tests of periodontal disease, the comparison of S-Bld. with H-III was carried out using the value of the PI and the GCF as markers. S-Bid. showed a superior property in the screening test from the standpoint of the balance between sensitivity and specificity, although sensitivity was a little low. H-III showed that only sensitivity was high, but specificity was quite low, that is, there was imbalance between sensitivity and specificity. Moreover, the false-positive rate of H-III was 70-90%. From these findings, S-Bld. is recommended as a screening test for periodontal disease.
有限責任中間法人日本口腔衛生学会の論文

歯周疾患スクリーニングテストに関する研究-唾液中潜血試験紙の有効性について-

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概要

有限責任中間法人日本口腔衛生学会 | 論文

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歯周疾患スクリーニングテストに関する研究-唾液中潜血試験紙の有効性について-

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概要

有限責任中間法人 日本口腔衛生学会 | 論文

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有限責任中間法人日本口腔衛生学会 | 論文