Fluoride and calcium levels in maternal and umbilical cord blood serum.

概要

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Fluoride is widely distributed throughout the body. In order to determine patterns of fluoride distribution in the body, ionic and whole fluoride levels as well as Ca levels (which have great affinity with those of fluoride) were determined in maternal and umbilical cord blood serum obtained during delivery.<BR>Both ionic and whole fluoride levels in maternal and cord blood serum showed almost normal patterns of distribution. Similar patterns were also observed for serum ionic and whole Ca levels. Although mean ionic fluoride levels in maternal and cord serum were comparable, whole fluoride levels in cord blood serum were significantly lower than those in maternal blood serum.<BR>A significant correlation was noted between ionic fluoride levels in cord blood serum and those in maternal blood serum. Ionic Ca levels in cord blood serum and those in maternal blood serum were also significantly correlated. In contrast, ionic and whole fluoride levels and ionic and whole Ca in maternal and cord blood serum were not significantly correlated with each other.<BR>These results suggest that the placental barrier blocks the transfer of maternal fluoride to some extent.
有限責任中間法人日本口腔衛生学会の論文