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• In order to clinically evaluate salivary duffer effect, a study was made of the resulting pH (the buffer pH) of the saliva when a specified volume of 0.1 N lactic acid was added to the sample according to the method of Dreizen et al. Attempts were also made to investigate factors which could affect the buffer capacity.<BR>Whole mouth saliva samples were collected during the so called resting state and during the mastication of a bolus of sugarless chewing gum from 54 children 4-9 years old and 135 dental students between the ages of 22 and 27 years.<BR>The buffer capacity was characteristic for each individual when 2.0 m<I>l</I> of whole saliva was titrated against 0.3 m<I>l</I> lactic acid. The relationship between the present buffer pH and the results of Dreizen et al. showed good agreement (r=0.92). The buffer capacity (buffer pH) was positively correlated with salivary flow rate in stimulated whole saliva (r=0.59, p<0.001), but not in resting saliva. In resting saliva, however, partial correlation analysis showed that the buffer capacity and the flow rate negatively correlated if the saliva pH factor was fixed. The mean buffer pH for the stimulated saliva of children was pH 5.41 (SD±0.51), and that of adults pH 5.72 (SD±0.50), the latter being significantly higher than the former. The difference in the mean buffer pH value was not significant before and after shaking saliva samples for a minute. 3-min aerat ion of the saliva sample after the addition of the acids caused a slight increase in buffer pH value with statistical significance. The buffer pH values of 5-min saliva samples collected during a continuous 30-min stimulation seemed to change mainly depending on the flow rate and to reach an apparent steady state within 15-20 min. Significant difference in mean salivary buffer measured at an identical time for three consecutive days was not found.<BR>Finally, significant negative correlation between the buffer capacity and the prevalence of caries was found in both children and adults.

• 有限責任中間法人 日本口腔衛生学会の論文

有限責任中間法人 日本口腔衛生学会 | 論文

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