キノリンカルボニトリルおよびイソキノリンカルボニトリルの有機酸との光化学反応(キノリンおよびイソキノリン誘導体の合成-7-)

概要

論文の詳細を見る
HMO calculation estimated a tendency of photochemical reaction of quinolinecarbo-nitriles and isoquinolinecarbonitriles in presence of organic acid. The tendency was proved by irradiation on these compounds in the presence of propionic acid and by identification of the reaction products. 2-Ethylquinoline, 2, 4-diethylquinoline, 2-phenylquinoline and 4-ethyl-2-quinolinecarbonitrile were given by the reaction of 2-quinolinecarbonitrile. 3-Quinolinecarbonitrile gave 2-ethyl-3-quinolinecarbonitrile, 4-ethyl-3-quinolinecarbonitrile, 3-cyano-4-ethyl-1, 4-dihydroquinoline and 2, 4-diethyl-3-quinolinecarbonitrile and 4- quinolinecarbonitrile gave 4-ethylquinoline, 2, 4-diethylquinoline and 2-ethyl-4-quinolinecarbonitrile as the reaction products. In isoquinoline series, 1-isoquinolinecarbonitrile gave 1-ethylisoquinoline, 1-phenylisoquinoline, 1, 4-diethylisoquinoline and 4-ethyl-1-isoquinolinecarbonitrile and 4-isoquinolinecarbonitrile gave 1-ethyl- 4-isoquinolinecarbonitrile and 4-cyano-l-ethyl-1, 2-dihydroisoquinoline.