Disproportionate Pulmonary Hypertension in a Patient with Early-onset Pulmonary Emphysema Treated with Specific Drugs for Pulmonary Arterial Hypertension
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概要
- 論文の詳細を見る
Severe pulmonary hypertension in chronic obstructive pulmonary disease (COPD) is referred to as 'disproportionate' because the elevated pulmonary artery pressure does not match the degree of air flow limitation. We report a 41-year-old man presenting with early-onset pulmonary emphysema and pulmonary hypertension with a mean pressure of 74 mmHg. Continuous intravenous epoprostenol led to marked hemodynamic improvement, and epoprostenol was successfully replaced with bosentan. The patient has been followed for 3 years without exacerbation. This is the first report demonstrating the long-term efficacy of specific drugs for pulmonary arterial hypertension in disproportionate pulmonary hypertension in COPD.
- 社団法人 日本内科学会の論文
著者
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Shimizu Masatoshi
Department Of Agricultural Chemistry Faculty Of Agriculture Niigata University
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Miwa Yoichi
Department Of Environmental Technology And Urban Planning Shikumi College Graduate School Of Enginee
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Takano Takatsugu
Department of Cardiology, National Hospital Organization Kobe Medical Center, Japan
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Imanishi Junichi
Department of Cardiology, National Hospital Organization Kobe Medical Center, Japan
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Miwa Yoichi
Department of Internal Medicine, National Hospital Organization Kobe Medical Center, Japan
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