A case of metastatic cutaneous cancer presenting various cutis symptoms.

概要

論文の詳細を見る
A 68-year-old Japanese man with various clinical features of metastatic skin cancer is described. He had suffered from ethmoid adenocarcinoma with cervical lymphnode metastasis. About 2 years later, multiple nodules developed on the neck, while at the same time maculopapules appeared on the anterior chest forming lace-like pattern. Biopsy specimen taken from the nodule revealed the diffusely scattered numerous tumor cells in the dermis. Histologic finding from the chest lesion showed the accumulation of tumor cells within the dermal vessels. No inflammatory change was observed in both specimens. Both anti-factor VIII and UEA-I immunohistological staining showed intense positive reaction on the vesseles. Although the specificity to blood vessel of anti-factor VIII and UEA-I antibody is not perfect, it seems to be blood vessels, because of the intensity and equality of their positive reaction.