乳房外 Paget 病の治療

概要

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Thirty-two patients with extramammary Paget's disease during a 15-year period were analyzed.The male to female ratio was 25 to 7, and the average age of the patients was 71.8 years. All the lesions were in the external genitalia or perianal regions. The treatment was composed of a histologically controlled, local wide excision, with regional lymphnode dissection when indicated. The 5-year survival rate was 77.1% and the 10-year rate 48.9%.Bilateral axillary skins in 26 of 32 patients were histologically examined; Paget's cells were also found in bilateral axillae of the 3 patients and in unilateral axilla in another 3 patients. The subclinical, axillary Paget's disease was considered to be a relatively frequent complication.