Tissue of extramammary Paget's disease. Histological examination of position showing decolorization spot of extramammary Paget's disease.

概要

論文の詳細を見る
Japanese patients with extramammary Paget's disease often show hypopigmented lesion just outside of erythema lesion where tumor cells grow in the epidermis. We made histological examination on the hypopigmented area of two specimens obtained surgically from two patients. As the results, the epidermis in the hypopigmented lesion has Paget's cells in a lower number than the reddish lesion. And the intraepidermal invasion of the tumor cells was clearly limited to the boundary between hypopigmented and clinically normal lesions in the two cases. Therefore, it may be possible that reduction of the width of excision from the edge of the hypopigmented lesion than reddish lesion.
日本皮膚悪性腫瘍学会の論文