治療困難な Paget 病の治療はやはり困難?

概要

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The present paper deals with the several factors that make treating Paget's disease and Paget's carcinoma difficult and their remedies. " Hard-to-treat" Paget's disease is still difficult to treat. However, with different techniques, it is possible to shif the limit line that defines the degree of difficulty of the treatment for these diseases.It is fundamental to clarify the boundary tumors prior to surgery by utilizing appropriate ointment therapy.Also, when treating Paget's carcinoma, the indication for lymphadenectomy is one of the important issues. In the future, it will be necessary to determine surgical treatment plans for primary cancer with respect to the degree of infiltration. Furthermore, it will be important to examine as to whether or not it will be possible to prevent distal lymphatic metastasis and death caused by primary cancer, by predicting attending lymphatic metastasis and administering appropriate treatment according to the degree of infiltration, based on various factors such as site, size, degree of infiltration, etc.In order to achieve these goals, because it is impossible to conduct a scientifically varid study in one hospital due to the small number of patients, it is therfore necessary to cooperate with other institutions.
日本皮膚悪性腫瘍学会の論文