Gastric emptying of solid meal in diabetic patients.
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The aim of this study was to investigate the relationship between the gastric emptying of solid meal and the severity of autonomic neuropathy in diabetic patients.The degrees of autonomic neuropathy (AN) were classified into mild AN and severe AN by heart rate variation with deep breathing.Gastric emptying was normal in mild AN patients, whereas marked delay was noted in severe AN patients. Patients with gastroparesis with gastric retention more than 80% at 150 minutes after ingestion of meal were noted only in severe AN patients. Patients with starting index slower than 60 minutes were seen in 8 among 13 severe AN patients, whereas 2/7 in mild AN patients and 1/14 in AN (-) patients had delayed starting index. Blood glucose level variations after ingestion of solid meal were small in severe AN patients.We conclude that the pathogenesis of diabetic gastroparesis is correlated with the impaired autonomic nerve function.
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- Gastric emptying of solid meal in diabetic patients.