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HBeAg and anti-HBeAb were detected by radioimmunoassay in 129 cases of chronic type B hepatitis.In acute hepatitis from HBsAg carriers (AH-C), persistent hepatitis (PH) and chronic active hepatitis (CAH), positive rate of HBeAg was high and many cases of these groups lost HBeAg or showed a seroconversion from HBeAg to anti-HBeAb during the follow-up period. Especially in two types of diseases, AH-C and PH, almost all cases showed seroconversion of HBeAg to anti-HBeAb during relatively short periods. On the other hand, HBeAg disappeared in about half cases of CAH, and a relatively long period was needed to losing of HBeAg in those cases indicating that CAH is a different pathological conditions from PH or AH-C.During follow-up period in this study two female cases of anti-HBeAb positive who showed disappearance of HBsAg, was observed.
- 財団法人 日本消化器病学会の論文