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Concentration of carcinoembryonic antigen (CEA) in the gastric juice of patients with various gastric diseases such as carcinoma (18 cases), ulcer (10 cases) and chronic gastritis (50 cases) was measured by radioimmunoassay using the Z-gel method. The CEA levels in the gastric juice were much higher in patients with carcinoma than in those with ulcer. The CEA levels measured by the Z-gel method correlated well with those measured by the Sandwich method.The CEA levels in the gastric juice were mostly much higher in the phase prior to the stimulation with tetragastrin than in the poststimulation phase. The CEA levels in the gastric juice were hardly influenced by both acidity and pepsin activity of the gastric juice but significantly influenced by its volume. The CEA levels in the gastric juice with large volume were mostly lower.
財団法人日本消化器病学会の論文