Immunoglobulin D-Lambda Type Multiple Myeloma Presenting with FDG-PET/CT Negative Bone Marrow Involvement
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概要
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We here report a rare case of a patient with IgD-lambda-positive multiple myeloma presenting with FDG-PET/CT negative bone marrow involvement. A 72-year-old man was admitted to our hospital for evaluation of a paravertebral tumor of the chest. Thoracotomy was performed and a histopathological evaluation of resected intrathoracic tumor demonstrated a plasmacytic neoplasma. Initially we thought that this case was a solitary plasmacytoma because there were no positive findings on postoperative FDG-PET/CT. However, bone marrow aspiration study demonstrated massive infiltration of myeloma cells (72%). It is necessary to recognize that IgD-lambda type myeloma cells may not be sufficiently metabolically active to form high uptake on FDG-PET/CT.
著者
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Shinohara Tsutomu
Department Of Pediatrics Kainan Hospital
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Yoshida Mitsuteru
Division of Respiratory Surgery, National Hospital Organization National Kochi Hospital, Japan
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Inayama Mami
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Hino Hiroyuki
Division of Thoracic Surgery, National Hospital Organization National Kochi Hospital, Japan
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Ogushi Fumitaka
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Machida Hisanori
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Hatakeyama Nobuo
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Okano Yoshio
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Hosokawa Emiko
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Abe Shuichi
Division of Pulmonary Medicine, National Hospital Organization National Kochi Hospital, Japan
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Naruse Keishi
Division of Pathology, National Hospital Organization National Kochi Hospital, Japan
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Iwahara Yoshihito
Division of Internal Medicine, National Hospital Organization National Kochi Hospital, Japan
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Ogushi Fumitaka
Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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Okano Yoshio
Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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Hatakeyama Nobuo
Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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Iwahara Yoshihito
Division of Internal Medicine National Hospital Organization National Kochi Hospital
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Hino Hiroyuki
Division of Respiratory Surgery, National Hospital Organization National Kochi Hospital, Japan
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Shinohara Tsutomu
Department of Clinical Investigation, National Hospital Organization National Kochi Hospital, Japan
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