Excess Copper Chelating Therapy for Wilson Disease Induces Anemia and Liver Dysfunction
スポンサーリンク
概要
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A 37-year-old man was diagnosed with Wilson disease at the age of 14. His first manifestations were neurological. He was treated with trientine for more than 10 years and suffered from anemia and liver dysfunction. Wilson disease is a genetic disorder characterized by accumulation of copper in the body. Excess copper is toxic, but copper is an essential trace element. Copper-binding ceruloplasmin is important for iron metabolism. Excess copper chelating treatment-induced anemia and iron deposition in the liver was suspected. Proper monitoring of copper status is important for the management of Wilson disease.
著者
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TABARU Akinari
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japa
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Harada Riko
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Harada Masaru
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Miyagawa Koichiro
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Honma Yuichi
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Hiura Masaaki
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Shibata Michihiko
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Matsuhashi Toru
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Abe Shintaro
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Honma Yuichi
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Abe Shintaro
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Harada Masaru
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Tabaru Akinari
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Hiura Masaaki
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
関連論文
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