Rapid Progression of Hepatocellular Carcinoma in a Patient with Autoimmune Hepatitis
スポンサーリンク
概要
- 論文の詳細を見る
We describe a case of a 69-year-old woman who developed rapidly progressive hepatocellular carcinoma (HCC) associated with autoimmune hepatitis (AIH) after a 7-year follow-up. Markers for viral hepatitis were negative. Serum tumor markers including alpha-fetoprotein and prothrombin induced by vitamin K absence II rose suddenly, and a large tumor was detected in spite of regular surveillance for HCC. Surgical treatment was performed. The resected liver specimen revealed well to moderately differentiated HCC. Ki67 staining showed rapid proliferation of the HCC. Although the incidence of HCC in patients with AIH has been unclarified, the possible complication by HCC must not be overlooked.
著者
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TABARU Akinari
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japa
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Shimajiri Shohei
Department Of Pathology And Cell Biology School Of Medicine University Of Occupational And Environme
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Yamaguchi Koji
The First Department of Surgery, Sapporo Medical University
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Harada Masaru
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Hiura Masaaki
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Japan
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Honma Yuichi
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Abe Shintaro
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Yamamoto Kayo
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Narita Ryoichi
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Okamoto Kohji
The First Department of Surgery, University of Occupational and Environmental Health, Japan
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Okamoto Kohji
The First Department of of Surgery, University of Occupational and Environmental Health School of Medicine, Japan
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Harada Masaru
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Tabaru Akinari
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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Hiura Masaaki
The Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan
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