THE ALTERATION OF ISOZYMIC PATTERNS IN LACTATE DEHYDROGENASE DURING ARTIFICIAL MATURATION OF RAT OVARY
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概要
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The alteration of LDH isozymic patterns was investigated electrophoretically during the maturation of rat ovaries artificially induced by gonadotrophins. In addition, the histochemical distribution of LDH activity was compared with the electrophoretic patterns. While five isozymes of LDH were demonstrated in the ovary of immature rats, isozyme-4 activity was highest. During the induced maturation of ovaries, the activity of isozyme-5 increased while isozyme-1, -2 and -3 activities decreased. On the other hand, the activity of isozyme-4 hardly varied. Histologically speaking, LDH activity was higher in the interstitial and thecal cells than in the granulosa. After formation of luteal bodies, the most intense activity appeared in luteal cells.
- 社団法人 日本内分泌学会の論文
著者
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Takikawa Hiroo
Department Of Pharmaceutical Chemistry Insitute Of Endocrinology Gunma University
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MATSUZAWA TOKIHIRO
Department of Pharmaceutical Chemistry, Institute of Endocrinology, Gunma University
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