ADENOHYPOPHYSIAL GLYCOGENOLYSIS IN RELATION TO ACTH RELEASE INDUCED BY INTRAPITUITARY INJECTION OF A PURIFIED HYPOTHALAMIC CRF

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概要

• 論文の詳細を見る

• Glycogenolysis in the anterior pituitary lobes of the rat was examined following intrapituitary microinjection of varying amounts of a purified pig hypothalamic CRF. The pituitary glycogen showed a significant decrease 20 mins. after direct injection of crude acetic acid extracts of the median eminence or a purified hypothalamic CRF. A greater depletion of the pituitary glycogen was obtained with increasing amount of CRF injected. It was concluded that glycogenolysis is involved in the enhanced ACTH secretion induced by CRF. Furthermore, from the analysis of the correlation between ACTH release and glycogen decrement, it was suggested that secretion of ACTH was biphasic, i.e., glycogenolysis-dependent and-independent.

• 社団法人 日本内分泌学会の論文

著者

• Hiroshige Tsutomu

  Department Of Physiology Hokkaido University School Of Medicine

• WAKABAYASHI ITIZI

  Department of Physiology, Hokkaido University School of Medicine

• YOSHIMURA KEIICHI

  Department of Physiology, Hokkaido University School of Medicine

• ITOH SHINJU

  Department of Physiology, Hokkaido University School of Medicine

関連論文

• Physiological Significance of Hypothalamic CRF in the Regulation of ACTH Secretion
• ADENOHYPOPHYSIAL GLYCOGENOLYSIS IN RELATION TO ACTH RELEASE INDUCED BY INTRAPITUITARY INJECTION OF A PURIFIED HYPOTHALAMIC CRF
• Postnatal Development of Circadian Rhythm of Corticotropin-Releasing Activity in the Rat Hypothalamus
• Diurnal Variation of Corticotropin-Releasing Activity in the Rat Hypothalamus
• ACTH RELEASE BY PURIFIED HYPOTHALAMIC CRF PREPARATION AS ASSAYED BY INTRAPITUITARY MICROINJECTION

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