Ovulation Inducing and Endometrial Proliferative Activities of some Progestins

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概要

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• Ovulation was blocked by a single subcutaneous injection of chlorpromazine hydrochloride (CPZ) in the proestrous rat running 4-day estrous cycle under the controlled illumination (14L:10D). Ovulation inducing activities of various progestins including 4 newly synthesized compounds in this institute, were examined in these CPZblocked rats and compared with their endometrial proliferative activities in the rabbit.<BR>Activities of endometrial proliferation in the rabbit, of ovulation induction in the rat, and of pregnancy maintenance in the rat were not always parallel in the progestins assayed.

• 社団法人 日本内分泌学会の論文

著者

• YAMAZAKI IWAO

  Biological Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

関連論文

• Comparison of Ovulation-inducing Effect between Estrogen and Progestin in the Ovulation-Blocked Rat by Chlorpromazine
• Ovulation Inducing and Endometrial Proliferative Activities of some Progestins

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