Effect of Somatostatin (Growth Hormone Inhibiting Factor: GIF) on TRH-induced TSH Release in Rats

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概要

• 論文の詳細を見る

• Intravenous preadministration of somatostatin (Growth Hormone Inhibiting Factor: GIF) inhibited TRH-induced TSH release in rats anesthesized by pentobarbitulate. There was dose dependent negative interaction between the inhibitory effect of GIF and releasing effect of TRH. TSH releasing effect of small dose of TRH was inhibited completely by preadministration of GIF, while large dose of TRH overcame the inhibitory effect of GIF. The mechanism responsible for inhibitory effect of GIF on TRH-induced release was discussed.

• 社団法人 日本内分泌学会の論文

著者

• BABA SHIGEAKI

  Second Department of Internal Medicine, Kobe University School of Medicine

• UTSUMI MASAFUMI

  Second Department of Internal Medicine, Kobe University School of Medicine

• MAKIMURA HIROYUKI

  Second Department of Internal Medicine, Kobe University School of Medicine

• YAMADA AKIHISA

  Second Department of Internal Medicine, Kobe University, School of Medicine

• TATEIWA MAKOTO

  Second Department of Internal Medicine, Kobe University, School of Medicine

• MORI HIDETARO

  Second Department of Internal Medicine, Kobe University, School of Medicine

• KUSAKA TAKAAKI

  Second Department of Internal Medicine, Kobe University, School of Medicine

• SAKODA MASAHIRO

  Second Department of Internal Medicine, Kobe University, School of Medicine

• UTSUMI MASAFUMI

  Second Department of Internal Medicine, Kobe University, School of Medicine

• MAKIMURA HIROYUKI

  Second Department of Internal Medicine, Kobe University, School of Medicine

関連論文

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• Insulin Binding and Degradation in Liver of Fed and Fasted Rats : Effect of Antiserum to Insulin-degrading Enzyme on Insulin Binding and Degradation
• Effect of Somatostatin (Growth Hormone Inhibiting Factor: GIF) on TRH-induced TSH Release in Rats

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