Lack of Inhibition of ACTH-induced. Aldosterone Stimulation by Des-asp<SUP>1</SUP>-, ileu<SUP>8</SUP>-angiotensin II in Man
スポンサーリンク
概要
- 論文の詳細を見る
In 5 normal men an intravenous injection of 0.5mg of synthetic<SUP>1-24</SUP>ACTH caused a significant increase in plasma aldosterone and a simultaneous intravenous infusion of 600ng/kg/min of des-asp<SUP>1</SUP>-, ileu<SUP>8</SUP>-angiotensin II (AIIIA) did not inhibit this increase. Since this dose of AIIIA is known to inhibit an angiotensin IIinduced increase in plasma aldosterone in normal men, the present results suggest that the ACTH-induced aldosterone stimulation is mediated by an adrenocortical receptor which is different from angiotensin II receptor.
- 社団法人 日本内分泌学会の論文
著者
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Imura Hiroo
Second Division Department Of Medicine Kyoto University School Of Medicine
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KONO TSUYOSHI
Second Division, Department of Internal Medicine, Kyoto University School of Medicine
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OSEKO FUMIMARO
Second Division, Department of Internal Medicine, Kyoto University School of Medicine
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IKEDA FUMITAKE
Second Division, Department of Internal Medicine, Kyoto University School of Medicine
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ENDO JIRO
College of Medical Technology, Kyoto University
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