A case report of pseudohypoparathyroidism (drezner's type I) associated with probable Bartter's syndrome.
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概要
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A 24-yr-old male patient had suffered from chronic tetany since school age. At the age of 20 tetanic convulsions occurred due to hypocalcemia. His mother also had chronic tetany due to pseudohypoparathyroidism. At the age of 24, hypocalcemia caused by pseudohypoparathyroidism was noted. Hypopotassemia persisted even when the hypocalcemia improved with the administration of 1α-hydroxycholecalciferol and calcium lactate. Other findings were normal blood pressure, high levels of plasma renin activity and serum aldosterone, a fall in blood pressure after angiotensin II antagonist infusion, blunted pressor response to angiotensin II infusion and hyperplasia of the juxtaglomerular cells. These results were compatible with Bartter's syndrome. Plasma prostaglandins E<SUB>2</SUB> and F<SUB>2α</SUB> in standing position were suppressed after indomethacin administration.<BR>To our knowledge this is thought to be the first report of a case of pseudohypoparathyroidism associated with probable Bartter's syndrome.
- 社団法人 日本内分泌学会の論文
著者
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Mitsuhashi Takehiro
Osaka City University Medical School
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Morii Hirotoshi
Osaka City University
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Kishimoto Taketoshi
Osaka City University Medical School
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Okahara Takeshi
Osaka City University Medical School
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Iba Kazuko
Osaka City University Medical School
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OKAHARA TAKESHI
Osaka City University, Departments of Pharmacology
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WADA MASASHISA
Osaka City University, Departments of Internal Medicine
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YASUMOTO RHOJI
Osaka City University, Departments of Urology
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HOJO KENJI
Osaka City University, Departments of Pathology
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MITSUHASHI TAKEHIRO
Osaka City University, Departments of Pathology
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KISHIMOTO TAKETOSHI
Osaka City University, Departments of Urology
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IBA KAZUKO
Osaka City University, Departments of Internal Medicine
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MORII HIROTOSHI
Osaka City University, Departments of Internal Medicine
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- A case report of pseudohypoparathyroidism (drezner's type I) associated with probable Bartter's syndrome.