Islet-Activating Protein (IAP) Reduces Bethanechol-Stimulated Release of Pancreatic Polypeptide in the Dog
スポンサーリンク
概要
- 論文の詳細を見る
The effect of islet-activating protein (IAP) purified from culture medium of <I>Bordetella pertussis</I> was examined in dogs. This was assessed by the levels of pancreatic polypeptide (PP) as well as the responses of plasma insulin and glucagon to a parasympathomimetic agent, bethanechol. Plasma responses of these pancreatic hormones were measured before and 5 days after IAP injection. Although IAP had no significant effect on the bethanechol-stimulated increase in plasma glucose, insulin and glucagon, the PP response to bethanechol was significantly reduced after IAP treatment compared with that before IAP (p<0.05). In conclusion, IAP significantly and selectively reduced bethanechol-stimulated PP release in the dog although the mechanism remained to be elucidated.
- 社団法人 日本内分泌学会の論文
著者
-
Toyoshima Hiroyuki
The Second Department Of Internal Medicine Yamagata University School Of Medicine
-
Tarui Seiichiro
The Second Department Of Internal Medicine Osaka University Medical School
-
NONAKA KYOHEI
The Second Department of Internal Medicine, Osaka University Medical School
-
HANAFUSA TOSHIAKI
The Second Department of Internal Medicine Osaka University Medical School
-
TOYOSHIMA HIROYUKI
The Second Department of Internal Medicine Osaka University Medical School
-
NONAKA KYOHEI
The Second Department of Internal Medicine Osaka University Medical School
関連論文
- Efficacy of combination therapy of interferon-α with ursodeoxycholic acid in chronic hepatitis C: A randomized controlled clinical trial
- Changes in serum hepatic fibrosis markers in biochemical responders to interferon therapy for chronic hepatitis C
- Acute Cholestatic Hepatitis Caused by a Probable Allergic Reaction to Paracetamol in an Adolescent
- Growth inhibiton and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge
- Angiotensin II stimulates the nuclear translocation of Smad2 and induces PAI-1 mRNA in rat hepatic stellate cells
- Home lactulose enema : prevention of hepatic encephalopathy at home
- Separate analysis of asialoglycoprotein receptors in the right and left hepatic lobes using ^Tc-GSA SPECT in patients with acute hepatic damage
- Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver
- Successful percutaneous radiofrequency ablation of adrenal metastasis from hepatocellular carcinoma
- Reduction of serum ghrelin concentration during interferon-α therapy in patients with chronic hepatitis C
- Expression of Notch signalling markers in bone marrow cells that differentiate into a liver cell lineage in a rat transplant model
- Transmission of hepatitis C virus quasispecies between human adults
- Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma
- CHARACTERISTICS OF CORONARY HEART DISEASE (CHD) IN FIMILIAL HYPERCHOLESTEROLEMIA (FH) AND ITS INCIDENCE IN FH WITHOUT CLINICAL CARDIAC SYMPTOM : Atherosclerosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -0378-DEMONSTRATION OF TWO SPECIES OF LDL PARTICLES IN PATIENTS WITH CHOLESTERL ESTER TRANSFER PROTEIN (CETP) DEFICIENCY
- COMPARISON OF PROGNOSIS BETWEEN FAMILIAL HYPERCHOLESTEROLEMIA PATIENTS WITH INTENSIVE TREATMENT AND THOSE WITHOUT TREATMENT : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- -531- STUDIES ON CLINICAL AND BIOCHEMICAL FACTORS WHICH AFFECT THE OCCURRENCE OF CORONARY ARTERY DISEASE (CAD) IN FAMILIAL HYPERCHOLESTEROLEMIA (FH) : INVESTIGATION IN THREE PAIRS OF SIBLINGS
- LATENT CARDIAC MANIFESTATION IN PATIENTS WITH PROGRESSIVE SYSTEMIC SCLEROSIS (PSS) AND RELATED TO CLINICAL COURSE : Cardiomyopathy (II) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- ANALYSIS OF CHEST X-RAY FILM AND ELECTROCARDIOGRAM IN OBSES PATIENTS : Exercise Test (II) : FREE COMMUNICATIONS (VI) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS OF CORONARY ARTERY DISEASE IN FAMILIAL HYPERCHOLESTEROLEMIA : Ischemic Heart Disease (VI) : FREE COMMUNICATIONS (VI) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- ANGIOGRAPHIC FINDINGS AND CLINICAL COURSE OF FAMILIAL HYPERCHOLESTEROLEMIA WITH CORONARY ARTERY DISEASE : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Ischemic Heart Disease (II)
- THE INVESTIGATION OF RISK FACTORS FOR DEVELOPMENT OF CORONARY ARTERY DISEASE IN PARTIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA : Ichemic Heart Disease (III) : 46th Annual Scientific Meeting, Japanese Circulation Society
- Lamivudine as an Alternative Therapy for Interferon-Resistant Chronic Hepatitis B and the Characteristics of Hepatitis B Virus : A Case Report
- CARDIAC FUNCTION IN MASSIVE OBESE SUBJECTS : CHANGES IN LEFT VENTRICULAR FUNCTION BY WEIGHT REDUCTION : Ventricular Function : 53 Annual Scientific Meeting, Japanese Circulation Society
- -0377-PROBUCOL (PB) CHANGES THE CELL POPULATION IN XANTHOMA OF FAMILIAL HYPERCHOLESTEROLEMIA (FH)
- -541- THE MECHANISM FOR ACCUMULATION OF ATHEROGENIC LIPOPROTEINS : CONTRIBUTION OF ENHANCED CHOLESTEROL ABSORPTION AND EXOGENOUS LIPOPROTEIN PRODUCTION IN THE INTESTINE
- -252- LIPOPROTEIN ABNORMALITIES IN FAMILIAL HYPERALPHALIPOPROTEINEMIA WITH SPECIAL REFERENCE TO CORONARY HEART DISEASE : Ischemic Heart Diseases : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCI
- LIPOPROTEIN ABNORMALITIES IN FAMILIAL HYPERALPHALIPOPROTEINEMIA ASSOCIATED WITH CORNEAL OPACIFICATION AND CORONARY HEART DISEASE : Atherosclerosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- RISK FACTORS OF RECURRENT MYOCARDIAL INFARCTION : Ichemic Heart Disease (I) : 46th Annual Scientific Meeting, Japanese Circulation Society
- -1131-MESSENGER RNA EDITING OF APOLIPOPROTEIN (APO) B IN HUMAN INTESTINAL CELL LINE CACO-2 : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -1130-GENETIC LOCUS CONTROLLING THE PARTICLE SIZE OF PLASMA LOW-DENSITY LIPOPROTEINS (LDL) IN MICE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- EFFECT OF DRUG TREATMENT ON LIPOPROTEIN METABOLISM IN FAMILIAL HYPER-ALPHA-LIPOPROTEINEMIA : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- LIPOPROTElN METABOLISM IN HYPER-ALPHA-LIPOPROTEINEMIA WITH DEFICIENCY OF CHOLESTERYL ESTER TRANSFER PROTEIN : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- Expression of the RNA-binding protein Musashi1 in adult liver stem-like cells
- Boiling Method for the Extraction of Gut Glucagon-like Immunoreactive Materials
- Various Phenotypes of Diabetes Mellitus as Ultimate Outcome of Acutely Developed Diabetic State Induced by Viral Infection
- Failure of Somatostatin to Decrease Blood Glucose by Suppression of Extrapancreatic Glucagon in Severely Diabetic Depancreatized Dogs
- Islet-Activating Protein (IAP) Reduces Bethanechol-Stimulated Release of Pancreatic Polypeptide in the Dog
- Impaired Response of Human Pancreatic Polypeptide to Insulin-Induced Hypoglycemia in Chronic Pancreatitis without Diabetes Mellitus
- The Effect of Secretin on Glucose-Stimulated Insulin Secretion in Man
- Changes in Distribution of Molecular Weight Forms of Biologically Active and Immunoreactive Adrenocorticotropic Hormone after Adrenalectomy in Rat Anterior Pituitary
- Dietary Therapy and Insulin Secretory Response to Glucose in Adult-Onset Non-Obese Diabetic Subjects
- Augmentation of ACTH-induced steroidogenesis in isolated rat adrenal cells by rat tissue extracts and by hormone preparations.
- Comparison of the Changes in Plasma Human Growth Hormone (HGH) and Immuno-Reactive Glucagon (IRG) after Intravenous and Subcutaneous Injection of Glucagon