Structure-Activity Relationship of Anthelmintic Cyclooctadepsipeptides

スポンサーリンク

概要

• 論文の詳細を見る

• The relationship between cyclooctadepsipeptides and their anthelmintic efficacy was examined by converting the natural products, PF1022A, PF1022E and PF1022H. Some analogues substituted at the para position of the phenyllactate moiety showed higher or equivalent activity against the parasitic nematode, Ascaridia galli in chicken when compared with the parent compounds. It is suggested that lipophilicity and the polar surface area, in addition to structural requirements of the derivatives, influenced the anthelmintic efficacy in vivo.

著者

• Ohyama Makoto

  Department Of Agricultural Chemistry Faculty Of Agriculture The University Of Tokyo:pharmaceutical T

• Atsumi Kunio

  Department Of Chemical Engineering Shizuoka University

• OKADA Yumiko

  Chemistry, Manufacturing & Control Research Laboratories, Meiji Seika Kaisha Ltd.

• TAKAHASHI Masaaki

  Chemistry, Manufacturing & Control Research Laboratories, Meiji Seika Kaisha Ltd.

• SAKANAKA Osamu

  Chemistry, Manufacturing & Control Research Laboratories, Meiji Seika Kaisha Ltd.

• MATSUMOTO Maki

  Chemistry, Manufacturing & Control Research Laboratories, Meiji Seika Kaisha Ltd.

関連論文

• Structure-Activity Relationship of Anthelmintic Cyclooctadepsipeptides
• CRITICAL AERATION RATE IN DISCHARGING AERATED SOLIDS THROUGH A VERTICAL STANDPIPE
• Total Synthesis of the Anthelmintic Cyclodepsipeptide, PF1022A
• Structure-Activity Relationship of Anthelmintic Cyclooctadepsipeptides
• Industrial expression equation for semisolid materials of solid-liquid mixture under constant pressure.
• Creep constants in expression of compressible solid-liquid mixtures.
• A STUDY OF CAKE FILTRATION:FORMULATION AS A STEFAN PROBLEM
• EXPRESSION OF THICK SLURRY OF TITANIUM DIOXIDE IN WATER:Determination of Expression Coefficient

スポンサーリンク