発癌プロモーター, テレオシジンの合成と生物活性
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概要
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This review deals with isolation, determination of the structure, conformational analysis and structure-activity relationships of teleocidins. Teleocidins exhibit potent tumor-promoting activity as well as many important biological activities connected with cell proliferation and cell differentiation. Teleocidins and diterpene esters containing TPA are classified as TPA-type promoters because they bind eaqually to the phorbol ester receptor and exhibit their biological activities. Structural requirements for tumor promoting activity, which are common in the TPA-type promoter, are also disccussed.
- 社団法人 有機合成化学協会の論文
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- 発癌プロモーター, テレオシジンの合成と生物活性
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