Chromosomal anomalies caused by preovulatory overripeness of the primary oocyte.

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概要

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• Effects of preovulatory overripeness of primary oocytes were studied cytogenetically in 2-cell rat embryos which developed from the ova unduely aged for 48 hours in mature follicles. Both aneuploids and mosaics increased significantly in the experimental group. It was clearly indicated that the delayed ovulation induces nondis j unction and anaphase lag of chromosomes during both the meiotic and first cleavage divisions. A significant increase of polyploidy was also proven as the result of the delay in ovulation. Its causal mechanism was confirmed to be polyspermy.

• 日本学士院の論文

著者

• Mikamo Kazuya

  Department Of Biological Sciences Asahikawa Medical College

• Kamiguchi Yujiroh

  Department Of Biological Sciences Asahikawa Medical College

• Funaki Kenji

  Department Of Applied Chemistry Graduate School Of Engineering Tohoku University

• FUNAKI Kenji

  Department of Biological Sciences, Asahikawa Medical College

関連論文

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• Chromosome Abnormality in Human Gametes by Exposure to Mutagens (特別企画 〔日本環境変異原学会〕第24回大会ミニシンポジウム) -- (ヒト集団の環境影響モニタリング)
• CHROMOSOMAL DAMAGE IN HUMAN SPERMATOZOA CAUSED BY IN VITRO IRRADIATION OF TRITIUM β-RAYS
• Chromosome aberration in human spermatozoa : its correlation with environmental mutagens(Symposium III : Relationship between environmental mutagenicity testing and cytogenetic research)(Abstracts of the 50th Annual Meeting of the Society of Chromosome Re
• Effects of Neonatal Ovarian X-irradiation in the Chinese Hamster. I. Correlation between the Age of Irradiation and the Fertility Span
• Palladium-catalyzed Direct C-H Bond Arylation of Simple Arenes with Aryltrimethylsilanes
• Effects of Neonatal Ovarian X-irradiation in the Chinese Hamster II. Absence of Chromosomal and Developmental Damages in Surviving Oocytes Irradiated at the Pachytene and Resting Dictyate Stages
• Chromosomal anomalies caused by preovulatory overripeness of the primary oocyte.

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