ANTIGENIC PROPERTIES OF MUCOSAL GLYCOPROTEIN FROM SWINE STOMACH

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概要

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• Mucosal glycoprotein, possessing a fucomucan-type carbohydrate composition, was isolated from swine stomach lining powder. It was found to possess the organ specificity as well as the species specificity, in addition to the blood-group activity. Such an antigenicity was not influenced by the treatment with various glycosidases (blood-group destroying enzymes). The alkaline borohydride treatment of the glycoprotein resulted a partial loss of the antigenicity when only the serine-carbo-hydrate linkages were cleavaged, but a complete loss when the threonine-carbo-hydrate linkages were cleavaged. On the basis of these experiments, the antigenic determinant was assumed to reside in the core protein including the carbohydrate linkage (threonine-galactosamine linkage) within the glycoprotein molecule.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• AKIYAMA KAZUKO

  Department of Legal Medicine, Kurume University School of Medicine

• KIMOTO FIJI

  Institute of Clinical Pathology, Kurume University School of Medicine

関連論文

• Immunochemical analysis of the species specific glycoprotein of the human red cell membrane.
• ANTIGENIC PROPERTIES OF MUCOSAL GLYCOPROTEIN FROM SWINE STOMACH

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