Hormonal Responses to Cold Exposure in Subjects with Vibration Syndrome

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概要

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• Responses of the autonomic nervous system and the endocrine system to cold exposure were investigated. The subjects were all males, between 41 and 69 years of age. Seventy subjects with the vibration syndrome and vibration-induced white finger (VWF (+) group), 70 subjects with the vibration syndrome without VWF (VWF(-) group) and 70 healthy subjects (control group) were individually matched according to age. The subjects remained in a cold room at 7°C for 30 minutes. Catecholamines, cyclic nucleotides, thyroid hormones, ACTH and cortisol were measured before and during cold exposure. The VWF (+) group and the VWF (-) group had larger % increases of plasma norepinephrine, cyclic AMP, cyclic GMP, T3 and T4 levels than the control group. These findings indicate that the responses of the autonomic nervous system and the thyroid system to cold exposure are greater in the subjects with the vibration syndrome.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• KONDO Hirokazu

  Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University

• Kohno Hideaki

  Department Of Neurosurgery Hiroshima University School Of Medicine

• Nakamoto Minoru

  Department Of Hygiene Yamaguchi University School Of Medicine

• Harada Noriaki

  Department Fo Hygiene Yamaguchi University School Of Medicine

• HARADA NORIAKI

  Departments of Public Health, Ehime University School of Medicine

• NAKAMOTO MINORU

  Departments of Public Health, Ehime University School of Medicine

• TANAKA MORISHIGE

  Departments of Central Research Laboratory, Ehime University School of Medicine

• Kondo Hirokazu

  Department of Cardiology, Tenri Hospital, Japan

• KONDO HIROKAZU

  Departments of Public Health, Ehime University School of Medicine

• KOHNO HIDEAKI

  Departments of Public Health, Ehime University School of Medicine

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