Prevalence in Sweden of Human Papillomavirus Type 16 Infectionin CIN II-III Cases Assessed by a PCR Method.
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概要
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The presence of human papillomavirus (HPV) 16 in cervical intraepithelial neoplasia (CIN)II-III cases was studied by means of a polymerase chain reaction (PCR) -based method applied to paraffin-embedded tissues. Twenty-two of 45 (49%) cases showed a positive signal determined by direct visualization on gel stained with ethidium bromide. Fourteen of these cases were confirmed by dot blot hybridization, which accords with a prevalence of HPV 16 infection in 31% of Stockholm patients with CIN II-III. The latter value is lower than that published elsewhere (Young et al. 1989; Maki et al. 1991 Skydberg et al. 1991).
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Hjerpe Anders
Department Of Immunology Microbiology Pathology And Infectious Diseases Division Of Pathology Huddin
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HASUO YASUYUKI
Department of Obstetrics and Gynecology, Kurume University School of Medicine
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Hjerpe Anders
Department of Pathology, Huddinge University Hospital
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CHUA KENG-LING
Department of Pathology, Huddinge University Hospital
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- Prevalence in Sweden of Human Papillomavirus Type 16 Infectionin CIN II-III Cases Assessed by a PCR Method.