白血球増多物質にかんする研究-2-

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As mentioned in the first report, it was Cysteine to show the most remarkable action according to the effect of mobilization about several substances to be considered to hold the blood cells increasing action.Now, I guess the leucocyte increasing (promoting) action of cysteine would relate with existence of the main reaction radical (-SH) and the side reaction radical (-NH2) in view of characteristics of the molecular structure and the reaction radical. In consideration that Thiol B1 (B1SH) and Penicillamine under the form of open ring of Thiamine and Penicilline combine with SH radical and NH2 radical in the similar orthotropic relationship with Cysteine, I made each of them for the purpose of investigating the above-mentioned fact and compared with the original forms by administering the fixed quantities of them to the healthy rabbits. As a result, B1SH and Penicillamine demonstrated the effect of mobilization more remarkably than that of Thiamine and Penicilline.Namely, it seems that existence of SH and NH2 radicals in the molecular structure and configuration relationship for the molecular structure have the important significance for demonstrating the leucocyte increasing action of the said substance and Cysteine
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