2年にわたりα-Fetoprotein のみが異常高値を示し, 肝切除後予後良好な Sclerosing type の肝細胞癌の1例

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A case of sclerosing hepatic carcinoma with a long-term preoperative elevated α-fetoprotein showing good postoperative course was reported. She was a 57 year-old woman who had no complaints and no abnormalities of the liver function tests except a remarkably elevatedα-fetoprotein of 10, 140ng/ml. During the 2 year observation, no tumors producingα-fetoproteins had been recognized. The tumor was found in the left lateral lobe of the liver on ultrasonography and CT-scan after 2 years observation. She was recieved the operation of left lobectomy of the liver Dec 3rd, 1982.<BR>The pathological findings revealed the caracteristics of the sclerosing hepatic carcinoma (SHC), acampanying, in parts, the lamellar fashion of fibrosis, so-called fibrolamellar carcinoma. This case looked different from SHC in some points, eg without pseudohyperparathyroidism, with good clinical course by far over 3 years after lobectomy.<BR>It is likely that the lamellar fashion of fibrosis may be checked the growth and progress of the SHC.