Clinical and pathological studies on hepatic fungus infections.

概要

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A statistical survey of hepatic fungus infections in Japanese pathological autopsies (1972-1981) was carried out. The incidence was 0.19% (521 cases) in the total 280, 532 autopsies, and 7.4% in overall fungus infections. Most of them were assumed to be partial phenomena of systemic fungus infections. The predominant type of infection was candidiasis.<BR>Thiry-five autopsy cases with hepatic fungus infections in our department were submitted for clinical and pathological investigations. Overt jaundice, increased S-GOT and S-GPT values were common clinical findings of cases.<BR>Macroscopically, capsulitis and multiple nodular lesions were the frequent evidence, and the latter was revealed in about half of the cases (51.4%) by surface inspection of the liver. By tissue reaction, the fungal lesions were classified into coagulation necrosis type (77.1%) and abscess-forming type (11.4%). It was concluded that coagulation necrosis type was the common lesion among the patients with severe immuno-deficiency, and abscess-forming type was frequent in immuno-resistant hosts, the infection route, and morphogenesis of the lesions were studied and the results were discribed.<BR>It was also pointed out that rare incidence of hepatic fungal lesions in liver cirrhosis, and the reason was discussed.
社団法人日本肝臓学会の論文