HBウイルスキャリアにおけるC型肝炎ウイルス重感染に関する研究-HBV濃厚感染地区における検討-
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概要
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HBV markers and antibodies (anti-C100 and anti-Core) to HCV were tested in 774 cases in an endemic area for liver diseases. Out of 774 cases, 97 cases (12.5%) were positive for HBsAg and 94 cases (12.1%) were positive for antibodies to HCV. Ten (10.3%) among 97 cases positive for HBsAg were superinfected with HCV.<BR>In 132 cases negative for HBsAg and with elevated ALT, 39 cases (29.5%) were positive for antibodies to HCV.<BR>HBV markers which reflect the HBV replication such as HBsAg titer, frequency of HBe antigenemia, DNA-P levels and inhibitory rate of anti-HBc titers were lower in the cases of superinfection than in HBV carriers negative for antibodies to HCV.<BR>These results suggest that HCV may reduce the replication of HBV in the cases of superinfection.
- 社団法人 日本肝臓学会の論文
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- HBウイルスキャリアにおけるC型肝炎ウイルス重感染に関する研究-HBV濃厚感染地区における検討-