肝性昏睡に対する交換血漿法の1治験例

概要

論文の詳細を見る
A woman, aged 44, complained of abdominal pain. She was disquiet. She went into grade III deep hepatic coma in two days. Plasma exchange was applied; under total heparinization, 400ml of her blood was removed from her radial artery, of that blood cells were cleaned with 5% fructose solution, and patient's plasma was depleted and replaced with frozen plasma, after then the clear blood was returned to her cubital vein. These procedures were repeated to 4500ml under mild general anesthesia (GO). She recovered within one month.<BR>Mcrits of this procedure may be as follows:<BR>1. This can be performed anywhere at any time, if astaff is able to take plasma or frozen plasma.<BR>2. Patients receive only homologous plasma, and not a large amount of fresh blood.<BR>3. Doctors and nurses are in safety, because lavage of toxic blood is made in the pack, namely, it is not made by centrifuge, and patient's blood flows through the complete closed system.
社団法人日本肝臓学会の論文