Analysis of Frequencies of Evoked Otoacoustic Emissions in Patients with Meniere's Disease

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Click-evoked otoacoustic emissions were recorded from 18 patients with Meniere's disease (MD), most of whom had low-frequency hearing loss (LFHL). The main frequencies obtained from patients with MD, where the maximum peak power of the emissions existed on the frequency spectra, were examined and compared with those obtained from patients with LFHL without MD and from subjects with normal hearing.<BR>The main frequencies of the emissions in patients with MD, ranged mainly from 0.8kHz to 1.1kHz, -somewhat lower than those in subjects with normal hearing (mainly from 1.0kHz to 1.4kHz). And in MD patients with LFHL, the main frequencies were lower than in patients with LFHL without MD. Furthermore, in 2 patients with MD, the main frequencies became higher when the osmotic diuretics, glycerol or isosorbide were administrated.<BR>These findings suggest that in ears with MD, low-frequency dominant emissions are elicited because of a modification of the oscillations of the basilar membrane in endolymphatic hydrops, which is considered to be the main pathological finding in MD. It is possible that the main frequencies of the emissions might rise when endolymphatic hydrops is reduced by treatment with osmotic diuretics.
日本めまい平衡医学会の論文