Association of partial Lipodystrophy and Sjögren's syndrome

概要

論文の詳細を見る
A 63-year-old female is described with Sjögren's syndrome without any evidence of rheumatoid arthritis or connective tissue disorder, but partial lipodystrophy had been marked since 10 years old. There was no abnormal findings on 50 gGTT and serum lipids. Immunological and histological study revealed positive SS-A antibody, positive lip-biopsy findings, normal renal biopsy finding and normal levels of serum complement that was reported common with partial lipodystrophy.Although, both of the Sjögren's syndrome and lipodystrophy are rareconditions, 3 cases of this association were reported already in the world. This case was understood 1st instance of lipodystrophy and Sjögren's syndrome in Japan. As there was good evidence of Sjögren's syndrome written in former report of lipodystrophy and immunological disorder on serum complement with high incidence in partial lipodystrophy, this intersting association of lipodystrophy and Sjögren's syndrome may not be coincidental.It would be helpfull studying evidence of sicca syndrome in patients with lipodystrophy easily diagnosed from the characteristic appearance to understand the relation of lipodystrophy and Sjögren's syndrome.
日本臨床免疫学会の論文