FENTANYL AND TOOTH PULP EVOKED RESPONSES IN THE SPINAL TRIGEMINAL NUCLEUS CAUDALIS REGION
スポンサーリンク
概要
- 論文の詳細を見る
Electrical activities evoked by tooth pulp stimulation were recorded in the subnucleus caudalis region of the spinal trigeminal nucleus, and the action of fentanyl, a short-acting narcotic, on these activities was investigated in the α-chloralose anesthetized cat. Fentanyl (20 or 40 μg/kg i.v.) depressed the first peak: and potentiated the second one of negative potentials evoked by pulp stimulation in the border area between the nucleus proprius (Pr) and the lateral reticular formation (LRF). Neurons, whose responses to pulp stimulation were depressed by fentanyl, were also predominantly localized in this region. Pulp-induced monophasic negative potential and spike discharges in the more ventro-medial portion of the LRF were not affected by fentanyl. The effect of fentanyl on cells in the marginal zone varied from unit to unit. The selective action of fentanyl on neurons in the border area between the Pr and the LRF may partially explain the analgesic action of fentanyl.
著者
-
Sakai Yutaka
Department Of Pharmacology National Defense Medical College
-
NISHIJIMA Yoshiaki
Medical Laboratory for Pharmacology, Central Research Laboratories, Sankyo Co., Ltd.
-
Sakai Yutaka
Department Of Information And Computer Sciences Faculty Of Engineering Saitama University
-
SAKAI Yutaka
Department of Pharmacology. The National Defense Medical College
関連論文
- Hydronephrosis caused by intra-abdominal abscess from cecal perforation by an ingested fish bone
- Transperineal extended biopsy improves the clinically significant prostate cancer detection rate : A comparative study of 6 and 12 biopsy cores
- PHARMACOLOGICAL CHARACTERIZATION OF POSTSYNAPTIC RECEPTORS FOR EXCITATORY AMINOACIDS IN PURKINJE CELL DENDRITES IN THE GUINEA PIG CEREBELLUM
- MODULATORY ACTIONS OF PROSTAGLANDINS ON CENTRAL SYNAPTIC TRANSMISSION
- Complicated urinary tract infection caused by Pseudomonas aeruginosa in a single institution (1999-2003)
- Increasing Muscle Strength and Mass of Thigh in Elderly People with the Hybrid-Training Method of Electrical Stimulation and Volitional Contraction
- INHIBITORY ACTIONS OF TAURINE AND METABOLITES ON PURKINJE CELLS IN THE CEREBELLUM
- FENTANYL AND TOOTH PULP EVOKED RESPONSES IN THE SPINAL TRIGEMINAL NUCLEUS CAUDALIS REGION
- TAURINE ACTS ON PRESYNAPTIC AUTORECEPTORS FOR GABA IN THE CEREBELLUM: EFFECTS ON Ca2+ INFLUX AND GABA RELEASE
- MANAGEMENT OF RETAINED SECUNDINES BY HYSTEROSCOPY
- COMPARATIVE STUDY ON THE EFFECTS OF HALOXAZOLAM AND ESTAZOLAM, NEW SLEEP INDUCING DRUGS, ON THE α- AND γ-MOTOR SYSTEMS
- EFFECT OF FENTANYL, A NARCOTIC ANALGESIC, ON TWO COMPONENTS OF THE JAW OPENING REFLEX
- BRAINSTEM ACETYLCHOLINE SENSITIVE NEURONS ACTIVATED BY CUTANEOUS IMPULSES IN CATS
- Computational algorithms and neuronal network models underlying decision processes
- Neuronal integration mechanisms have little effect on spike auto-correlations of cortical neurons
- Single P-element insertional mutagenesis in Drosophila melanogaster.
- Studies on the muscle relaxation effects of ethyl loflazepate (CM6912) and evaluation as an anti-anxiety drug.
- Inhibitory effect on 3H-diazepam binding and potentiating action on GABA of ethyl loflazepate, a new minor tranquilizer.