EFFECTS OF CYTOCHROME C ON THE LIVER FUNCTION OF AGED RATS
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概要
- 論文の詳細を見る
Observed to be associated with impairment of liver function in aged rats were: increased lipid peroxides in the liver and serum, diminishing hepatic glutathionc and decreases in mitochondrial respiratory activity and cytochrome content. Spontaneous failure of hepatic functions in aged animals was significantly ameliorated by the administration of cytochrome c. It is suggested that the underlying mechanism lies in the versatile ability of cytochrome c to reduce lipid peroxides, increase the hepatic glutathione content and activate mitochondrial function.
- 社団法人 日本薬理学会の論文
著者
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OHNISHI Haruo
Research Laboratory, Mochida Pharmaceutical Co., Ltd.
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TSUKUDA Shigeru
Research Laboratory, Mochida Pharmaceutical Co., Ltd.
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OGAWA Nobuhisa
Research Laboratory, Mochida Pharmaceutical Co., Ltd.
関連論文
- EFFECTS OF CYTOCHROME C ON LIPID AND SUGAR METABOLISM IN AGED RATS
- EFFECTS OF CYTOCHROME C ON THE LIVER FUNCTION OF AGED RATS
- EFFECT OF CYTOCHROME C ON CARBON TETRACHLORIDE DAMAGE TO THE LIVER
- HISTOPATHOLOGICAL STUDIES OF THE EFFECTS OF CYTOCHROME C ON CARBON TETRACHLORIDE-INDUCED LIVER DAMAGE AND ON THE LIVERS OF AGED RATS
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