GLYCEMIC EFFECTS OF SOLANINE IN RATS

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概要

• 論文の詳細を見る

• It has been widely recognized that solanine (Fig. 1) is contained in Solarium species, especially in fresh potato sprouts as a toxic alkaloid. There have been reports concerning sola n i ne, namely, Kline <I>et al</I>. (1) reported that potato sprouts were shown to be toxic to pregnant rats when fed at a level of 10% of the diet. Solanine and solanidine, aglycon of solanine, inhibit human plasma cholinesterase <I>in vitro</I> (2, 3). No other pharmacological and biochemical studies on toxicities of solanine have been published. The present investigation was undertaken to determine the alteration of blood sugar level of rat treated with solanine. Hyperglycemia has been reported as one feature of poisoning by some toxic substances, i.e., guthion (4), paracetamol (5), parathion (6) and amphetamine (7). It seemed possible, therefore, that changes of disturbance of carbohydrate metabolism.

著者

• 佐藤 哲男

  Department of Pharmacology and Toxicology, Institute of Food Microbiology, Chiba University

関連論文

• Inhibition of Tryptophan Pyrrolase of Rats by Phenols, Tryptophan Analogs and Hydrazine Derivatives
• EFFECTS OF THIAMINE PROPYL DISULFIDE ON TRYPTOPHAN PYRROLASE IN RATS
• ELECTROSHOCK, LIVER SEROTONIN LEVEL AND TRYPTOPHAN PYRROLASE ACTIVITY IN RATS
• GLYCEMIC EFFECTS OF SOLANINE IN RATS

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