EFFECTS OF SOME TRANQUILLIZING AGENTS ON BRAIN NORADRENALINE AND DOPAMINE LEVELS OF SHOCKED RATS

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概要

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• In the previous report (1), the authors showed that the brain noradrenaline level in rat was induced to elevation, in the state of electric shock, compared with that in non-treated animals. On the other hand, pretreatment with some tranquil lizing agents, chlorpromazine, azacyclonol inhibited the increase of noradrenaline level in shocked state, while, chlordiazepoxide had no effect on noradrenaline level.<BR> In addition to the previous paper, other tranquillizing agents, tetrabenazine, thioridazine and cyproheptazine were employed in this experiment in order to examine their effect on both noradrenaline and dopamine levels of rat brain in abnormal environment, i.e., electrically shocked state.

• 公益社団法人 日本薬理学会の論文

著者

• 佐藤 哲男

  Institute of Chemical Pharmacology, Faculty of Pharmaceutical Science, Hokkaido University School of Medicine

• 岩本 多喜男

  Institute of Chemical Pharmacology, Faculty of Pharmaceutical Science, Hokkaido University School of Medicine

• 徳光 幸子

  Institute of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Hokkaido University School of Medicine

• 佐藤 哲男

  Institute of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Hokkaido University School of Medicine

関連論文

• EFFECTS OF CHLORPROMAZINE, AZACYCLONOL AND CHLORDIAZEPOXIDE ON BRAIN CATECHOLAMINE CONTENTS OF STRESSED RATS
• EFFECTS OF SOME TRANQUILLIZING AGENTS ON BRAIN NORADRENALINE AND DOPAMINE LEVELS OF SHOCKED RATS
• EFFECTS OF CHLORPROMAZINE, TETRABENAZINE AND AZACYCLONOL ON BRAIN SEROTONIN LEVEL OF SHOCKED RATS

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