EFFECTS OF NICOTINAMIDE AND INSULIN ON GLYCOSYLATED HEMOGLOBIN AND BLOOD GLUCOSE IN THYROIDECTOMIZED STREPTOZOTOCIN-DIABETIC RATS
スポンサーリンク
概要
- 論文の詳細を見る
The present study deals with the effects of nicotinamide and insulin on glycosylated hemoglobin (HbA<SUB>1</SUB>) and blood glucose in thyroidectomized streptozotocin (STZ)-diabetic male rats. Nicotinamide (500 mg/kg body wt., i.p.) significantly decreased the levels of HbA<SUB>1</SUB> and blood glucose in both STZ-treated (65 mg/kg body wt., i.v.) intact and STZ-treated thyroidectomized animals. Administration of NPH-insulin recovered hyperglycemia, and the increased HbA<SUB>1</SUB> in thyroidectomized STZ-diabetic rats to control levels.
- 社団法人 日本薬理学会の論文
著者
-
TSUKAHARA Fujiko
Department of Pharmacology, Tokyo Women's Medical University, School of Medicine
-
Fujii Emiko
Department Of Pediatrics School Of Medicine Tokushima University
-
Nomoto Teruko
Department Of Pharmacology Tokyo Women's Medical College
-
NOMOTO Teruko
Department of Pharmacology, Tokyo Women's Medical College
-
TSUKAHARA Fujiko
Department of Pharmacology, Tokyo Women's Medical College
関連論文
- Molecular Characterization of the Mouse mtprd Gene, a Homologue of Human TPRD: Unique Gene Expression Suggesting Its Critical Role in the Pathophysiology of Down Syndrome^1
- Identification and Cloning of a Novel cDNA Belonging to Tetratricopeptide Repeat Gene Family from Down Syndrome-Critical Region 21q22.2
- Patients with West syndrome whose ictal SPECT showed focal cortical hyperperfusion
- Effect of S-Ethylisothiourea, a Putative Inhibitor of Inducible Nitric Oxide Synthase, on Mouse Skin Vascular Permeability
- The Effect of Acute Cold Exposure and Norepinephrine on Uncoupling Protein Gene Expression in Brown Adipose Tissue of Monosodium Glutamate-Obese Mice
- EFFECT OF INTRACEREBROVENTRICULAR ADMINISTRATION OF CHLORPROMAZINE ON THE SERUM LEVEL OF FREE FATTY ACIDS IN RATS
- SEX DIFFERENCES IN GLUCOSE METABOLISM, CARDIOVASCULAR AND INFLAMMATORY RESPONSES IN STREPTOZOTOCIN-DIABETIC ANIMALS
- ACTIONS OF THYROTROPIN-RELEASING HORMONE IN THE CENTRAL NERVOUS SYSTEM
- EFFECTS OF NICOTINAMIDE AND INSULIN ON GLYCOSYLATED HEMOGLOBIN AND BLOOD GLUCOSE IN THYROIDECTOMIZED STREPTOZOTOCIN-DIABETIC RATS
- Roles of Biogenic Amines in the Hypothalamo-Pituitary-Thyrid System in the Rats
- NOREPINEPHRINE DETECTION IN THE ANTERIOR PITUITARY OF MICROWAVE IRRADIATED RATS
- INVOLVEMENT OF CENTRAL CHOLINERGIC SYSTEM IN DECREASE OF SERUM FATTY ACIDS AFTER INTRACEREBROVENTRICULAR ADMINISTRATION OF CHLORPROMAZINE
- Central Nervous System Mediated Stimulation by Thyrotropin-Releasing Hormone of Microcirculation in Thyroid Gland of Rats
- SEX DIFFERENCE OF METABOLISM IN RAT LIVER AFTER TESTOSTERONE PROPIONATE ADMINISTRATION
- Changes in glycosylated hemoglobin in short- and semi long-term streptozotocin-diabetic mice and rats.
- Identification and Cloning of a Novel cDNA Belonging to Tetratricopeptide Repeat Gene Family from Down Syndrome-Critical Region 21q22.2.
- Molecular Characterization of the Mouse mtprd Gene, a Homologue of Human TPRD: Unique Gene Expression Suggesting Its Critical Role in the Pathophysiology of Down Syndromel.