Suppressive effects of tritoqualine on cell growth and collagen secretion in fibroblasts.
スポンサーリンク
概要
- 論文の詳細を見る
The effects of tritoqualine (TRQ) on established cell lines of fibroblasts, Balb/3T3 and 3T6, were investigated with respect to growth and collagen secretion. TRQ suppressed growth rate in the log phase and inhibited collagen secretion in the stationary phase of both cell lines. However, TRQ was not cytotoxic because of lack of influence on cell maintenance in the stationary phase. These effects of TRQ are thought to be very important as a mechanism of inhibitory action against liver fibrosis in chronic liver injury in rats.
- 公益社団法人 日本薬理学会の論文
著者
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YUASA Satoshi
Bioscience Laboratory, Research Center, Mitsubishi Chemical Ind. Ltd.
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SUDOH Atsuko
Bioscience Laboratory, Research Center, Mitsubishi Chemical Ind. Ltd.
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UMEZU Kohei
Bioscience Laboratory, Research Center, Mitsubishi Chemical Ind. Ltd.
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