ライフスタイルおよび医療行動が好中球機能に及ぼす影響 : ―中国天津市在住高齢者のNBT還元試験による貪食・活性酸素生産能による好中球機能評価―

概要

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Objective: In this study, we investigated the relationships of neutrophil functions with lifestyle factors (namely, subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived status health) and health behavior in the Chinese urban elderly. Methods: We performed a health survey of the elderly aged 65 years or older living in Tianjin. The subjects were 42 males (69.1±4.1 years old) and 41 females (69.1±4.1 years old). Investigations of subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived health status were performed. The phagocytosis and superoxide productivity of neutrophils were measured by the nitroblue tetrazolium (NBT) reduction method. In addition, leukocyte count and serum total protein (TP) level were examined. Results: The investigations revealed the associations of health behavior (p<0.05) and self-perceived health (p<0.10) with the balance between phagocytosis and subsequent superoxide production. Conclusions: The present study revealed that there were correlations of neutrophil functions with lifestyle factors (subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived status health) and health behavior in the Chinese urban elderly.