鼓室階外リンパ酸素分圧に関する研究 : 第1報Control, Anoxia負荷及び炭酸ガス負荷

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Oxygen transport to the inner ear is carried out by the inner ear blood flow and diffusion, and oxygen is necessary to maintain the inner earfunction. Particulary perilymph of scala tympani ought to be the pool of the oxygen which is utilized in the organ of Corti. The oxygentension of scala tympani war studied on guinea pig in anoxia, CO2 gas inhalation and autonomic nerve poisoning, oxygentension of scala tympani was 26.4mmHg in an average and lower than that of cerebrospinal fluid. The anoxia for 4 minutes and ligature of the inner ear artery for 3 minutes showed the same titre of oxygentension. From these results, it is likely that oxygentension of perilymph depends on the inner ear artery.Oxygentension of perilymph and cerebrospinal fluid was increased by inhalation pure O2 gas. When CO2 gas was mixed in an increasing way, the oxygentension was further increased and reached to the maximum by inhalation of 85%O2+15%CO2 gas. From this result the responses of inner ear vessel and cerebral vessel to CO2 gas inhalation seemed to be the samen.
社団法人日本耳鼻咽喉科学会の論文