ラット耳道腺腫瘍に関する研究(第2報) : ラット耳道腺腫瘍に対する制癌剤効果の検討

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概要

• 論文の詳細を見る

• Ear duct tumor induced in rats by DMBA and DAS shows a very high incidence within a rather short period, appearing similar histological features of squamous epithel-origin. Besides, the tumor has well been established its microscopical stage of tumorigenesis and its advancement toward macroscopical formation of tumor. Rat ear duct tumor induced by DMBA and DAS is thus far superior to the other chemically induced tumors so far employed as experimental models.Effects of BLM and 5-FU against the ear duct tumors induced in rats by DMBA and DAS were studied. BLM inhibited strongly the tumors, while 5-FU proved to have no inhibitory effect. It was also revealed that BLM exerted its inhibitory effect on growth of tumor, failing to play its action in earlier stage of tumorigenesis.

• 社団法人 日本耳鼻咽喉科学会の論文

著者

• 原田 壽利

  関西医科大学耳鼻咽喉科学教室

関連論文

• ラット耳道腺腫瘍に関する研究(第2報) : ラット耳道腺腫瘍に対する制癌剤効果の検討
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• 先天性舌披裂症(congenital bifid tongue)の1例

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