Tone Burstによる蝸電図SPの基礎的研究

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概要

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• The present paper has been performed experimentarily to study the recording site within the cochlea of the ECoG-SP with tone burst. Guinea pigs were anesthetized with Urethane (Ethyl Carbamate) and controlled with the respirator. After opening the tympanic bulla, micro-hole were made with microdrill under operating microscope, corresponding to scala media (SM), scala tympani (ST) and scala vestibule (SV) on the bony shell. The recording electrodes were taken from the following 11 points; the tympanic bulla (TB), the round window (RW), SM, ST and SV of the 1st, 2nd and 3rd cochlear turns. Tungsten microelectrode insulated with Vinyl Chloride was used for SM recording, a silver needle electrode for TB and other intracochlear recordings and silver-ball electrode for RW recording. A silver-silver chloride electrode was placed on the neck muscle as a reference electrode. Tonal stimuli consisting of 300msec repetition period were given as an open system. The frequencies of tone burst were 0.5kHz, 1kHz, 2kHz, 4kHz and 8kHz whose rise decay time and duration were set at 10msec and 45msec respectively. The responses were observed on CR-oscilloscope and/or obtained with ATAC-201 signal processor, analysis time of which was selected at 100msec. The SP obtained from 11 recording locations, were discussed with each other about polarity, input-output function and recovery process after anoxia. The results were followings: 1) The polarity of SP obtained from TB were negative for all tested frequencies and intensities and its input-output function were shown to be monotonic with sound intensity. 2) The SP obtained from other specific electrode locations changed with stimulus condition. Some of them were monotonic and others were non-monotonic. 3) The SP obtained from the RW and the 1st turn of the ST were identical. 4) The SP obtained from TB showed no close relationship with specific recording sites involving RW in its polarity and intensity function. 5) The SP obtained from the RW and the 1st turn of the ST are quite similar and its polarity was positive at higher frequency tone. According to our results, we have come to the conclusion that the SP obtained from TB are summed responses of the SP generated within the cochlea including the upper cochlear turn.

• 社団法人 日本耳鼻咽喉科学会の論文

著者

• 棚橋 汀路

  名古屋大学医学部附属病院分院耳鼻咽喉科

• 田中 八郎

  名古屋大学医学部耳鼻咽喉科学教室

• 棚橋 汀路

  名古屋大学医学部付属病院分院耳鼻咽喉科

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