内リンパ水腫に対するOsmotic induction法の実験的研究

概要

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The influence of the osmotic induction method on the endolymphatic hydrops was investigated in guinea pigs. 1. Obliteration of the emdolymphatic sac resulted in the production of hydrops in both cochlea and vestibular organs. 2. Either an infusion of saturated, sodium chroride solution into the middle ear or placement of crystal NaCl on the round window niche induced an appearance of exudates in the perilymphatic space. When a great amount of crystal NaCI was placed the retrograde degeneration of the organ of Corti in the basal turn was observed and both hyperemia of, and bleeding from, the modiolar vessels were also observed any tension-decresing effect on Reissners membranes. 3. The infusion of saturated NaCl solution into the middle ear of the animals with endolymphatic hydrops decreased the tension of Reisners membranes, which first observed in the basal turn. Twenty four hours later, this treatment developed the collapse in the endolymphatic space of the basal turn and retrograde degeneration in the organ of Corti. The same treatment caused stronger disturbance in the inner hair cells than in the outer hair cells, and deformity of the membraneous canal in the vestibular organs.
社団法人日本耳鼻咽喉科学会の論文