慢性副鼻腔炎に対する各種新抗生剤の局所応用

概要

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111 cases of patients with chronic sinusitis were treated locally with new antibiotics such as Phenoxyethyl penicillin, Dimethoxyphenyl penicillin, Pyrrolidinomethyl tetracycline, Kanamycin and partially with Leucomycin.The following results were obtained: Marked improvement 42.3%, moderate improvement 29.7%, slight improvement 20.7% and ineffective 7.2%. But, the long term results were lowered to about one-third of the results obtained above.These effects were rather closely related to the age of patients, course of onset, pathological changing of nasal cavity and sorts of bacteria in middle meatus. Furthermore, there was some difference between the antibiotics employed.From the comparative investigation of the sensitivity against staphylococcus which was obtained from the secretion of middle meatus the effects show that the selection of antibiotics must be made more carefully.
社団法人日本耳鼻咽喉科学会の論文