DETERMINATION OF ALLERGEN-SPECIFIC IgG ANTIBODY IN THE PATIENTS WITH NASAL ALLERGY

概要

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IgG antibodies specific to allergen were determined by enzyme-linked allergosorbent assay (ELASA) in 30 patients with nasal allergy who had positive reactions in the intractaneous test for house dust or mites. In this experiment, ELASA was modified and allergen-linked polyacrylamide beads were used to for a solid phase. The following results were obtained. 1) Determination of the allergen-specific IgG antibody by ELASA using polyacrylamide beads was easier and simpler. 2) In the patients who proved positive with the intracutaneous reaction with house dust, the level of IgG antibody specific to the house dust was not so high bofore desensitization therapy (continuous intracutaneous injection of allergen). 3) The level of the specific IgG antibody was elevated in almost 80% of the patients who received the desensitization therapy. 4) The remissions of the clinical sympotmes were clearly demonstrated in the typical cases of the patients whose specific IgG levels were elevated by the desensitization therapy.
名古屋市立大学の論文
1984-12-25