頸動脈洞圧刺激の中枢神経系への影響
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概要
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The responses through carotid sinus reflex usually occur during an operation of neck. A common response is a decrease of blood pressure and bradycardia. However, a few patients (especially those with hypertension who are over 50 years of age) show a dangerous response probably due to the excitation of higher brain center. The influence of the pressure stimulation of carotid sinus upon central nervous system was examined in cat by recording muscle spindle discharges of ankle extensors and E.E.G. of the motor cortex. At the same time, blood pressure, E.K.G. and the pattern of respiration were recorded with a nine channel penwriting recorder. Following results were obtained : 1) Depression of blood pressure caused by pressure stimulation depend on the depth of anesthesia (ether or pentobarbital).2) Under a light ether anesthesia, amplitude of E.E.G. of motor cortex was descreased by pressure stimulation. On the other hand, under a light pentobarbital anesthesia, spindle waves appeared on motor cortex and the hippocampal arousal waves disappeared by the stimulation. 3) Muscle spindle discharges were decreased by pressure stimulation. 4) After the pressure stimulation, depression of blood pressure and bradycardia were elicited earlier than inhibition of muscle spindle discharges and slowing of E.E.G. 5) Blood pressure decrease was usually elicited in the lower intensity of stimulation than the muscle spindle depression.
- 社団法人 日本耳鼻咽喉科学会の論文