蛋白質工学のための構造解析
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概要
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The site-directed mutagenesis opens the doors to investigations of the fundamental nature of proteins and to additions of new valuable characters to proteins. In such circumstances, it is desired to speed up the X-ray structure analyses of protein molecules. Area detectors are expected as one of the promising outcomes of recent technical developments and it can collect diffraction intensities many times more rapidly than current instruments. One can design a new protein from the many results of these protein structure determinations and also of the closely related protein structures. [J. Cryst. Soc. Jpn. 29, 27 (1987) ] .
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